Yubikey is an interesting premise: mix a smart card security dongle with OpenID and solve your web security access problems (at least for sites that support OpenID). It looks like Yubikey also supports RADIUS and PAM support. It's open source, so technically, you can pair pretty much any security protocol with it.
At first blush it looks like a pretty solid device. Security Now's Steve Gibson found it very cool (technical term, I know), and others haven't disagreed. For $30.00 USD, it's not a bad solution to check out as another means of authentication. What's your take on it?