A study conducted by Palo Alto Networks and reported in the New York Times Bits blog says that problems ranging from unauthorized proxy redirects, masked applications, and the consequences of moving corporate data out to the Internet and back are some of the challenges facing organizations seeking to use these forward-thinking technologies today.
As security administrators must develop more granular network controls and protection and police certain applications and network transport protocols, every exciting new technology that uses the latest web features might also be another weakening of your organization's protection, and must be considered closely.
For a counterpoint to the article, also check out Ross Mayfield's blog post, Fear Sells 2.0.
Source, Bits, a NYT blog.