In this article by the founder of GNU, Richard Stallman, he warns us that trusting our data to Google and the other cloud software companies is folly, and that we're setting ourselves up for a horrible fall. He sites privacy and lock-in as two main points to consider.
Stallman's not entirely wrong, and yet, several businesses are moving more and more of their work into the web-delivered model. Even mighty Microsoft is seeming to be trending towards web-powered technology. It's rumored that the dreaded Service Pack DVDs are going the way of the dodo, in favor of automated, web-delivered updates. As a guy who does almost all of his applications via the web, I'm still not convinced it's the devil. Does your company trust Google with your office computing needs or your mail? How are you approaching this?